Tadarise Black 80 mg is marketed as a tadalafil-based product for erectile dysfunction (ED) in adult men. Tadalafil belongs to a class of medicines called PDE5 inhibitors. It works by increasing blood flow to the penis during sexual stimulation, helping some men achieve and maintain an erection. Tadalafil must not be taken with nitrate medicines, such as nitroglycerin, because the combination can cause a potentially dangerous drop in blood pressure. Men with cardiovascular disease, low blood pressure, or those taking alpha-blockers or blood-pressure medicines should discuss tadalafil with a healthcare professional before treatment.