Extra Super Zhewitra is commonly marketed as a combination medicine containing vardenafil and dapoxetine. Vardenafil is a PDE-5 inhibitor used for erectile dysfunction (ED), while dapoxetine is a short-acting SSRI used for premature ejaculation (PE). The exact strengths can vary by manufacturer, so check the packaging before use. Vardenafil works by increasing blood flow to the penis during sexual stimulation. Dapoxetine affects serotonin signalling and may help delay ejaculation and improve ejaculation control.